Table 2.

Overall survival from diagnosis of BM in the discovery cohort according to laboratory parameters at univariate and multivariable analyses

	Univariate Analysis (log rank test)		Multivariable Analysis (Cox regression model)
	Median OS, mo	P-value	HR	95% CI	B	P-value
Hemoglobin
<LLN*	4	<.001	1.280	1.100–1.491	0.247	.001
NR	8
>ULN	11		0.927	0.413–2.084	-0.076	.855
Platelet count
<LLN*	4	<.001	1.365	1.068–1.744	0.311	.013
NR	7
>ULN	5		1.199	0.970–1.481	0.181	.093
WBC
<LLN	4	.005	1.217	0.845–1.751	0.196	.292
NR	7
>ULN	6		1.084	0.931–1.262	0.081	.299
Albumin
<LLN*	4	<.001	1.191	1.010–1.405	0.175	.038
NR	7
Creatinine
<LLN	3	.018	1.261	0.748–2.123	0.232	.384
NR	7
>ULN	6		1.044	0.891–1.222	0.043	.596
LDH
NR	8	<.001
>ULN*	4		1.515	1.303–1.760	0.415	<.001
CRP
NR	9	<.001
>ULN*	5		1.525	1.312–1.774	0.422	<.001

Parameters marked with * were included in LabBM score calculation.