Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 May 4;45(Web Server issue):W495–W500. doi: 10.1093/nar/gkx384

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 1. — An infographic illustration of C-SPADE web-tool and its functionalities. (A) Various types of biological drug screening assays (biochemical, cell-based, cell-free or target-based assays) can be analyzed. (B) The key functionalities implemented in C-SPADE. (C) The input consists of a tab-delimited text file of drug screening data, with compound names and bioactivity values, where a wide range of activity measurements are supported. (D) On the server-side, the compound name is used to retrieve the compound structural information from the PubChem database and various compound features are calculated using the RDKit package. (E) The client-side options provide an interactive interface to visualize and customize the compound clusters. (F) The output visualization from C-SPADE can be either shared with collaborators or downloaded as publication-quality images or as a Newick tree file.