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. 2017 Aug 24;12(8):e0183590. doi: 10.1371/journal.pone.0183590

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Fig 5 — (A) VWF antigen levels in plasma of F8^+/y (WT) vs F8^-/y mice (n = 9). (B) VWF multimer analysis of plasma samples from F8^+/y vs F8^-/y mice (n = 5). (C) ADAMTS13 levels in plasma of F8^+/y vs F8^-/y mice (n = 7). (D) VWF antigen levels in plasma of F8^-/y mice, 2h after tail vein injection of recombinant FVIII (Kogenate) at a dose of 1.5 U per 30g body weight or with 0.9% NaCl solution as a vehicle control (n = 11,10,12). All data were expressed as means ± SEM. Statistical comparisons were performed using the Student’s t-test or one-way ANOVA, * p< 0.05, ** p<0.01.