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. 2017 Aug 24;12(8):e0183263. doi: 10.1371/journal.pone.0183263

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© 2017 Uppu et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 10 — (A) A. baumannii did not develop resistance to QCybuAP but a very high and rapid resistance was observed for known antibiotics with an increase in MIC up to 64 fold after 28 passages. Macromolecules delay the development of resistance to both the known antibiotics with only 8-fold increase in MIC even after 28 passages. (B) E. coli developed rapid resistance to colistin and tetracycline but not to Qn-prAP and Qn-prAP + tetracycline.