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. 2017 Aug 24;12(8):e0183481. doi: 10.1371/journal.pone.0183481

Fig 5. Influence of recombinant human collagen-based microspheres on conduction slowing mediated by a paracrine mechanism.

Fig 5

A: Activation map of a monolayer of NRVM co-cultured with pASC (left), and an activation map of a monolayer of NRVM cultured with pASC loaded microspheres (right). Conduction velocity is determined along the white arrows perpendicular to isochronal (black) lines. Lower panels: the effects on B: conduction velocity and C: conduction heterogeneity. * indicates p< 0.001 compared to the NRVM + pASC. Number of replicates per experimental condition is indicated in the bar-graphs. Abbreviations; MS: microspheres, NRVM: neonatal rat ventricular myocytes, and pASC: porcine adipose tissue-derived stromal cells.