Table 1. Summary of the human PGM1 homologs.
Paralog (EC No.) | Name | Lineage* | UniProtKB | PDB entry (organism) | No. resi | pI |
---|---|---|---|---|---|---|
PGM1 (5.4.2.2) | phosphoglucomutase | animals, plants, fungi | P36871 | 5EPC (human) | 562 | 6.3 |
PGM2 (5.4.2.7) | phosphopentomutase | animals, fungi | Q96G03 | - | 612 | 6.3 |
PGM2L1 (2.7.1.106) | G16P synthase | vertebrates | Q6PCE3 | - | 622 | 6.8 |
PGM3 (5.4.2.3) | phosphoacetyl-glucosamine mutase | animals, plants, fungi | O95394 | 2DKA, 2DKC, 2DKD (C. albicans), 4BJU (A. fumigatus) | 542 | 5.8 |
PGM5 | aciculin | vertebrates | Q15124 | - | 567 | 6.8 |
*Only eukaryotic lineages included.
Sequence ID, no. residues, and pI correspond to the major transcript of each protein. EC: Enzyme Commission; PDB: Protein Data Bank.