Table 3.
Commonly used medication associated with gut microbiota alterations. Table from Imhann et al. Gut 2016.
| Medication category | Taxon | Direction |
|---|---|---|
| Antibiotics | g__Holdemania | Increased |
| Antidepressants (SSRI, SNRI, mirtazapine and TCA) | f__Bacteroidaceae | Increased |
| Antidepressants (SSRI, SNRI, mirtazapine and TCA) | g__Bacteroides | Increased |
| Antidiabetic medication (both oral and insulin) | o__Bacillales | Increased |
| Changes bowel movement/stool frequency* | p__Firmicutes | Decreased |
| Changes bowel movement/stool frequency* | o__Clostridiales | Decreased |
| Changes bowel movement/stool frequency* | c__Clostridia | Decreased |
| Changes bowel movement/stool frequency* | g__Coprococcus | Decreased |
| Changes bowel movement/stool frequency | o__Bacteroidales | Increased |
| Changes bowel movement/stool frequency | p__Bacteroidetes | Increased |
| Changes bowel movement/stool frequency | f__Bacteroidaceae | Increased |
| Changes bowel movement/stool frequency | g__Bacteroides | Increased |
| Cholesterol lowering medication (statins)* | o__Bacillales | Increased |
| Cholesterol lowering medication (statins) | g__Dorea|s__longicatena | Decreased |
| Cholesterol lowering medication (statins) | g__Ruminococcus | Increased |
| Triglyceride lowering medication (Fibrates)* | g__Ruminococcus|s__gnavus | Increased |
Note. All associations are statistically significant at FDR < 0.05
k__, kingdom; p__; phylum; c__, class; o__, order; f__, family; g__, genus; s__, species.
*
Statistically significant FDR<0.05 after correction for PPI use.