Fig 3. Protein-protein interaction network of the S. cerevisiae orthologs of the C. albicans proteins affected by CaPpz1 deletion.

The network of proteins listed in Table 3 and the two budding yeast phosphatase paralogs Ppz1 and Ppz2 was generated using String 10.5 with default settings at medium stringency. The network nodes are proteins identified by the gene name, while the lines are edges representing functional associations based on different types of evidence according to the String color coding scheme. The black boxes highlight the proteins which are associated with biofilm formation. The black arrows represent the two putative substrates of Ppz1.