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. 2017 Aug 24;12(8):e0182900. doi: 10.1371/journal.pone.0182900

Table 1. Demographic, patient and hospital characteristics.

Characteristic Total (n = 55,942) Crohn’s disease (n = 35,788) Ulcerative colitis (n = 20,154) p-value
Mean age (years) 47.8 45.8 51 <0.001
Age group (years)
18–35 18,528 (33.1%) 12,745 (35.6%) 5783 (28.7%) <0.001
36–50 13,626 (24.4%) 9396 (26.3%) 4230 (21.0%)
51–65 12,359 (22.1%) 7668 (21.4%) 4691 (23.3%)
>65 11,429 (20.4%) 5979 (16.7%) 5450 (27.0%)
Sex
Male 25,050 (44.9%) 15,711 (43.9%) 9349 (46.4%) <0.001
Female 30,862 (55.2%) 20,077 (56.1%) 10,805 (53.6%)
APR-DRG Risk of Mortality
Minor 36,193 (64.7%) 23,552 (65.8%) 12,641 (62.7%) <0.001
Moderate 11,800 (21.1%) 7569 (21.1%) 4231 (21.0%)
Major 6282 (11.2%) 3729 (21.1%) 4231 (21.0%)
Extreme 1666 (3.0%) 938 (2.6%) 728 (3.6%)
Smoking 14,549 (26.0%) 10,412 (29.1%) 4137 (20.5%) <0.001
Depression 9710 (17.4%) 6621 (18.5%) 3089 (15.3%) <0.001
Anxiety 7387 (13.2%) 5063 (14.1%) 2324 (11.5%) <0.001
Depression and anxiety 3649 (6.5%) 2558 (7.1%) 1091 (5.4%) <0.001
Opioid dependence 880 (1.6%) 676 (1.9%) 204 (1.0%) <0.001
Cannabis dependence 713 (1.3%) 539 (1.5%) 174 (0.9%) <0.001
Length of stay (mean days) 5.5 5.3 5.9 <0.001
Total charges (mean USD) 43,390 41,345 47,060 <0.001
Primary payer
Medicare 17,531 (31.1%) 10,703 (29.9%) 6648 (33.0%) <0.001
Medicaid 8078 (14.5%) 5606 (15.7%) 2472 (12.3%)
Private 23, 546 (42.1%) 14, 898 (41.7%) 8648 (43.0%)
Self-pay 3812 (6.8%) 2598 (7.3%) 1214 (6.0%)
No charges 611 (1.1%) 418 (1.2%) 193 (1.0%)
Other 2478 (4.4%) 1519 (4.2%) 959 (4.8%)
Median income quartiles for patient’s ZIP code
Quartile 1 (lowest income) 12, 947 (23.5%) 8538 (24.2%) 4409 (22.2%) <0.001
Quartile 2 14,082 (25.5%) 9225 (26.2%) 4857 (24.5%)
Quartile 3 14,303 (25.9%) 9065 (25.7%) 1214 (6.0%)
Quartile 4 (highest income) 13,795 (25.0%) 8447 (23.9%) 5348 (26.9%)
Teaching status of hospital
Metropolitan teaching 22, 458 (40.1%) 14,210 (39.7%) 8248 (40.9%) <0.001
Metropolitan non-teaching 29, 429 (52.6%) 18, 848 (52.7%) 10, 581 (52.5%)
Non-metropolitan 4055 (7.2%) 2730 (7.6%) 1325 (6.6%)
Hospital volume
Low 5757 (10.3%) 3670 (10.3%) 2087 (10.4%) 0.344
Medium 13, 378 (23.9%) 8629 (24.1%) 4749 (23.6%)
High 36,807 (65.8%) 23,489 (65.6%) 13,318 (66.1%)
Disease complications
Intraabdominal fistula or abscess 4397 (7.9%) 4397 (12.3%) -
Perianal fistula or abscess 1309 (2.3%) 1309 (3.7%) -
Stricture 6348 (11.3%) 5565 (15.5%) 783 (3.9%) <0.001
Bowel obstruction 3808 (6.8%) 2766 (7.7%) 1042 (5.2%) <0.001
Gastrointestinal bleeding 3433 (6.1%) 1881 (5.3%) 1552 (7.7%) <0.001
Clostridium difficile colitis 3926 (7.0%) 1679 (4.7%) 2247 (11.1%) <0.001
Hypovolemia 9445 (16.9%) 5481 (15.3%) 3964 (19.7%) <0.001
Electrolyte disturbance 16,274 (29.1%) 9740 (27.2%) 6534 (32.4%) <0.001
Anemia 5733 (10.2%) 3190 (8.9%) 2543 (12.6%) <0.001
Malnutrition 5950 (10.6%) 3677 (10.3%) 2273 (11.3%) <0.001
Hospitalization characteristics
Lower endoscopy 12,266 (21.9%) 5773 (16.1%) 6493 (32.2%) <0.001
Abdominal CT scan 2218 (4.0%) 1419 (4.0%) 799 (4.0%) 0.997
Blood transfusion 6335 (11.3%) 3294 (9.2%) 3041 (15.1%) <0.001
Parenteral nutrition 2541 (4.5%) 1840 (5.1%) 701 (3.5%) <0.001
Small bowel resection 1324 (2.4%) 1159 (3.2%) 165 (0.8%) <0.001
Colectomy (partial or total) 2828 (5.1) 2117 (5.9%) 711 (3.5%) <0.001
Any surgery performed 3722 (6.7%) 2891 (8.1%) 831 (4.1%) <0.001
Elective surgery 1807 (3.2%) 1358 (3.5%) 549 (2.7%) <0.001
Urgent surgery 1495 (2.7%) 1298 (3.6%) 197 (1.0%) <0.001
Index admission, no subsequent readmission 35,935 (64.2%) 21,387 (59.8%) 14,548 (72.2%) <0.001
Index admission, subsequently readmitted 7745 (13.8%) 5384 (15.0%) 2361 (11.7%)
Repeat readmission 12262 (21.9%) 9017 (25.2%) 3245 (16.1%)