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. 2017 Aug 24;12(8):e0182900. doi: 10.1371/journal.pone.0182900

Table 2. IBD risk factors for 30-day readmission.

Characteristic Not readmitted within 30 days (n = 40,643) Readmitted within 30 days (n = 3037) Univariate p-value Multivariate OR (95% CI)
Mean age (years) 49.3 44.8
Crohn’s disease 24,826 (61.1%) 1,944 (64.0%) 0.001 1.09 (1.00–1.18)
Ulcerative colitis 15,817 (38.9%) 1,091 (36.0%) 0.001 Ref
Age group (years)
18–35 12.053 (29.7%) 1,207 (29.8%) <0.001 Ref
36–50 9.719 (23.9%) 736 (24.3%) 0.67 0.75 (0.68–0.82)
51–65 9,582 (23.6%) 592 (19.5%) <0.001 0.59 (0.53–0.66)
>65 9,289 (22.9%) 500 (16.5%) <0.001 0.45 (0.39–0.53)
Sex
Male 17,932 (44.1%) 1,429 (47.1%) 0.002 1.16 (1.07–1.25)
Female 22,711 (55.9%) 1,606 (52.9%) 0.002 Ref
APR-DRG Risk of Mortality
Minor 26,114 (64.3%) 2,007 (66.1%) 0.037
Moderate 8,602 (21.2%) 638 (21.0%) 0.852
Major 4,678 (11.5%) 331 (10.9%) 0.314
Extreme 1,248 (3.1%) 59 (1.9%) <0.001
Smoking 10,300 (25.3%) 851 (28.1%) 0.001 1.09 (1.00–1.19)
Depression 6,498 (16.0%) 557 (18.4%) 0.001 NS
Anxiety 4,854 (11.9%) 437 (14.4%) <0.001 1.17 (1.01–1.36)
Depression and anxiety 2,342 (5.8%) 222 (7.3%) <0.001 NS
Opioid dependence 453 (1.1%) 60 (2.0%) <0.001 1.40 (1.06–1.86)
Cannabis dependence 474 (1.2%) 48 (1.6%) 0.042 NS
Weekend admission 8,488 (20.9%) 641 (21.1%) 0.758
Length of stay (mean days) 5.4 5.8
Total charges (mean USD) 43,230 42,193
Primary payer
Medicare 12,912 (31.8%) 860 (28.4%) <0.001 Ref
Medicaid 4,878 (12.0%) 509 (16.8%) <0.001 NS
Private 17,979 (44.3%) 1,258 (41.5%) 0.003 0.78 (0.69–0.89)
Self-pay 2,653 (6.5%) 223 (7.4%) 0.079 0.83 (0.69–0.99)
No charges 404 (1.0%) 41 (1.4%) 0.059 NS
Other 1,769 (4.4%) 141 (4.6%) 0.446 NS
Median income quartiles for patient’s ZIP code
Quartile 1 (lowest income) 8,914 (22.3%) 762 (25.5%) <0.001 Ref
Quartile 2 10,195 (25.5%) 756 (25.3%) 0.83 0.90 (0.81–1.0)
Quartile 3 10,494 (26.2%) 750 (25.1%) 0.178 0.88 (0.79–0.98)
Quartile 4 (highest income) 10,429 (26.1%) 722 (24.1%) 0.023 0.88 (0.79–0.98)
Teaching status of hospital
Metropolitan teaching 20,887 (51.4%) 1,654 (54.5%) 0.001 Ref
Metropolitan non-teaching 16,563 (40.8%) 1,189 (39.2%) 0.088 0.92 (0.85–1.0)
Non-metropolitan 3,193 (7.9%) 192 (6.3%) 0.002 0.75 (0.64–0.89)
Hospital volume
Low 4,400 (10.8%) 286 (9.4%) 0.016
Medium 9,685 (23.8%) 758 (25.0%) 0.153
High 26,558 (65.3%) 1,991 (65.6%) 0.774
Disease complications
Intraabdominal fistula or abscess 2,830 (7.0%) 274 (9.0%) <0.001 1.32 (1.15–1.52)
Perianal fistula or abscess 866 (2.1%) 75 (2.5%) 0.213
Stricture 4,542 (11.2%) 310 (10.2%) 0.104
Bowel obstruction 2,896 (7.1%) 173 (5.7%) 0.003 NS
Gastrointestinal bleeding 2,528 (6.2%) 183 (6.1%) 0.675
Clostridium difficile colitis 2,562 (6.3%) 220 (7.2%) 0.04 NS
Hypovolemia 6,719 (16.5%) 586 (19.3%) <0.001 1.23 (1.11–1.35)
Electrolyte disturbance 11,505 (28.3%) 941 (31.3%) 0.001 1.16 (1.06–1.26)
Anemia 4,023 (9.9%) 334 (11.0%) 0.05 NS
Malnutrition 3,750 (9.2%) 393 (13.0%) <0.001 1.37 (1.22–1.54)
Hospitalization characteristics
Lower endoscopy 9,685 (23.8%) 745 (24.6%) 0.371
Abdominal CT scan 1,649 (4.1%) 110 (3.6%) 0.242
Blood transfusion 4,438 (10.9%) 379 (12.5%) 0.008 1.19 (1.06–1.34)
Small bowel resection 1,054 (2.6%) 39 (1.3%) <0.001
Colectomy (partial or total) 2,278 (5.6%) 107 (3.5%) <0.001
Any surgery performed 3,004 (7.4% 127 (4.2%) <0.001 0.57 (0.33–0.96)
Elective surgery 1,741 (4.3%) 66 (2.2%) <0.001 NS