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Coupling efficiency of different ligands determined by potentiometric titration
| Modification | μmol/mg nanogel | Coupling efficiency |
|---|---|---|
| R1 (Unmodified) | 1.85 ± 0.05 | N/A |
| R2 (AEHS) | 1.33 ± 0.01 | 71.8 ± 1.5% |
| R3 (AGS) | 1.36 ± 0.09 | 73.7 ± 3.3% |
| R4 (NMEDA) | 1.66 ± 0.13 | 90.1 ± 5.4% |
| R5 (ED) | 1.68 ± 0.11 | 90.9 ± 6.5% |
