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a) UV/Vis spectra recorded during the titration of a mixture of 2 (4.97 μM) and rhodamine 6G (4.97 μM) with methamphetamine (6, 0 – 219 μM) in 20 mM NaH2PO4 buffered water (pH 7.4). b) Plot of absorbance versus [2] fitted to a competitive binding model with Ka = (4.3 ± 1.0) × 106 M−1. c) ITC thermogram recorded during the titration of 2 (87 μM) in the cell with 12 (0.93 mM) in the syringe. d) Fitting of the data to a 1:1 binding model with Ka = (6.8 ± 0.1) × 105 M−1.
