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Interaction between transcription factors NF-κB and AP-1, which bind to their respective DNA target sequences and facilitate chromatin remodeling. In the nucleus, NF-κB binds to cognate sites and synergistically interacts with proteins to redistribute chromatin remodeling complexes on chromosomal DNA. This change affects the cellular developmental fate by altering protein occupancy in the proximal and distal gene regulatory regions in a cell-specific and gene-specific fashion.
