2.
Comparison of demographic characteristics of 120 melanoma patients and 120 healthy controls and comparison between the two subgroups of 52 MetM and 68 NMetM patients
| Characteristics | All melanoma cases n=120 | Healthy controls n=120 | OR (CI) (melanomas vs. healthy controls) | P (melanomas vs. healthy controls) | MetM n=52 | NMetM n=68 | OR (CI) (MetM vs. NMetM) | P (MetM vs. NMetM) |
| Age, years, mean±SD | 59.1±12.8 | 56.8±11.8 | – | 0.110a | 60.2±12.1 | 58.3±13.4 | – | 0.503a |
| Age <50 years, n (%) | 34 (28.3) | 37 (30.8) | 0.89 (0.51–1.54) | 0.671 | 11 (21.1) | 23 (33.8) | 0.52 (0.23–1.21) | 0.127 |
| Males, n (%) | 65 (54.2) | 65 (54.2) | 1.00 (0.60–1.66) | 1.000 | 32 (61.5) | 33 (48.5) | 1.70 (0.81–3.53) | 0.156 |
| BMI, kg/m2, mean±SD | 25.7±3.89 | 24.4±3.35 | – | 0.010a | 26.1±3.81 | 25.4±3.94 | – | 0.392a |
| BMI >25.0 kg/m2, n (%) | 63 (52.5) | 52 (43.3) | 1.44 (0.87–2.40) | 0.155 | 30 (57.7) | 33 (48.5) | 1.45 (0.70–2.99) | 0.319 |
| BMI >30.0 kg/m2, n (%) | 16 (13.3) | 5 (4.2) | 3.54 (1.25–10.0) | 0.012 | 9 (17.3) | 7 (10.3) | 1.82 (0.63–5.27) | 0.263 |
| Born in FVG region, n (%) | 99 (82.5) | 100 (83.3) | 0.94 (0.48–1.85) | 0.864 | 40 (76.9) | 59 (86.8) | 0.51 (0.20–1.32) | 0.160 |
| All 4 grand-parents born in FVG region, n (%) | 85 (70.8) | 83 (69.2) | 1.08 (0.62–1.88) | 0.778 | 35 (67.3) | 50 (73.5) | 0.74 (0.34–1.63) | 0.457 |
| Elementary school (5 study years), n (%) | 17 (14.2) | 8 (6.7) | 2.31 (0.96–5.58) | 0.057^ | 10 (19.2) | 7 (10.3) | 2.07 (0.73–5.89) | 0.164 |
| Low high-school (8 study years), n (%) | 34 (28.3) | 21 (17.5) | 1.86 (1.01–3.45) | 0.046 | 18 (34.6) | 16 (23.5) | 1.72 (0.77–3.83) | 0.182 |
| High-school (13 study years), n (%) | 54 (45.0) | 42 (35.0) | 1.52 (0.90–2.55) | 0.114 | 21 (40.4) | 33 (48.5) | 0.72 (0.35–1.49) | 0.374 |
| University level (laurea and/or master and/or PhD), n (%) | 15 (12.5) | 49 (40.8) | 0.21 (0.11–0.40) | <0.001 | 3 (5.8) | 12 (17.6) | 0.29 (0.08–1.07) | 0.051^ |
| Continued | ||||||||