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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Hepatology. 2017 Jul 18;66(3):953–968. doi: 10.1002/hep.29215

Figure 4. Effect of PTX3 in high precision-cut liver slices.

Figure 4

Liver slices from mice treated with CCl4 were incubated with or without PTX3 and stimulated with LPS. a) Gene expression of Ccl20, Ccl5, Mcp-1 and Tnf-α in liver slices after incubation for 1 hour with rPTX3 (500 ng/mL) (n=4) or vehicle with or without addition of LPS (25 μg/mL) (n=4) for an additional 6 hours. #p<0,05 compared with control; *p<0,05 compared with LPS induction. b) Tissue culture supernatant levels of lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in (n=4) from cultures of liver slices pre-incubated with rPTX3 or vehicle for 1 hour before LPS stimulation for 6 hours #p<0,05 compared with control; *p<0,05 compare with liver slices treated with LPS.