Table 3.
Age at Menopause and Risk of Hearing Loss Among Postmenopausal Women, Nurses’ Health Study II (1991-2013)
| Age at Menopause |
Cases | Person-years | Age-adjusted RR (95% CI) |
Multivariable- adjusted RRa (95% CI) |
|---|---|---|---|---|
| Natural | ||||
| <50 years | 2,589 | 122,303 | 1.00 (ref) | 1.00 (ref) |
| 50+ years | 3,399 | 140,178 | 1.06 (1.00, 1.13) | 1.10 (1.03, 1.17) |
| Surgical | ||||
| <50 years | 1,597 | 73,764 | 1.00 (ref) | 1.00 (ref) |
| 50+ years | 301 | 12,674 | 0.96 (0.84, 1.09) | 1.00 (0.87, 1.15) |
P-interaction = 0.07
a
Multivariable models adjusted for age; race; body mass index; waist circumference; physical activity; smoking; hypertension; diabetes; intake of alcohol, folate, vitamin B12, vitamin C, magnesium, long chain omega-3 fatty acids, trans-fat, beta-carotene and beta-cryptoxanthin; ibuprofen use; acetaminophen use; tinnitus; parity; and duration of hormone therapy.