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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Jun 29;37(9):1628–1639. doi: 10.1161/ATVBAHA.117.309184

Figure 3. GLUT3 deletion leads to decreased platelet function.

Figure 3

(A) Survival curve following collagen/epinephrine induced pulmonary embolism, n=22. (B) Washed platelets were incubated on collagen or fibrinogen coated chamber slides under static conditions in the presence or absence of 0.1U/mL thrombin (IIa), and stained with phalloidin (green) for cytoskeletal changes, scale 5μm, n=4. (C) Spreading was quantified as summarized in the bar graphs, n=4. (D) Representative image of clot retraction assay performed in diluted whole blood stimulated with thrombin and data quantification (E), n=4. Data are mean±SEM. *P<0.05, **P<0.01 vs. control same treatment; 2-way ANOVA followed by Tukey’s multiple comparison post hoc test (E); Student’s t test (C); Log-rank (Mantel-Cox) test (A.).