Table 3.

Results from simple and multiple regression models for outcomes of spine and femoral neck BMD Z-scores in adults with IBMFS.

	Univariable Models				Multivariable Models
	Spine BMD Z-score		Femoral Neck BMD Z-score		Spine BMD Z-score		Femoral Neck BMD Z-score
	R2	P-value	R2	P-value	Adj R2	P-value	Adj R2	P-value
All variablesa					40.5%	0.001	65.1%	<0.001
Height	20.2%	0.007	22.7%	0.005	---	0.13	---	0.015
HSCT	8.9%	0.081	21.1%	0.007	---	0.043	---	<0.001
Glucocorticoids	4.2%	0.24	2.7%	0.36	---	0.14	---	0.12
Diagnosis (FA vs non-FA)	14.1%	0.026	11.9%	0.0496	---	0.19	---	0.006
Hypogonadism	36.4%	<0.001	42.2%	<0.001	---	0.003	---	<0.001

^aHeight, HSCT, steroids, diagnosis, hypogonadism.

R² = coefficient of determination; indicates the percentage of the variability of the outcome that is explained by the model.

HSCT: Hematopoietic stem cell transplantation

FA: Fanconi anemia