Table 17.
ToxIC 2016 agent entries—cardiovascular
| N (%) | |
|---|---|
| Beta blockers | 181 (27.7) |
| Metoprolol | 70 (10.7) |
| Propranolol | 56 (8.6) |
| Atenolol | 24 (3.7) |
| Carvedilol | 16 (2.4) |
| Labetalol | 7 (1.1) |
| Miscellaneousa | 8 (1.2) |
| Sympatholytics | 169 (25.8) |
| Clonidine | 141 (21.6) |
| Guanfacine | 28 (4.3) |
| Calcium channel antagonists | 113 (17.3) |
| Amlodipine | 63 (9.6) |
| Diltiazem | 23 (3.5) |
| Verapamil | 18 (2.8) |
| Nifedipine | 8 (1.2) |
| Miscellaneousb | <5 (<0.8) |
| Angiotensin-converting enzyme (ACE) inhibitors | 52 (8.0) |
| Lisinopril | 47 (7.2) |
| Miscellaneousc | 5 (0.8) |
| Cardiac glycosides | 46 (7.0) |
| Digoxin | 44 (6.7) |
| Digitoxin | 2 (0.3) |
| Other antihypertensives and vasodilators | 32 (4.9) |
| Prazosin | 16 (2.4) |
| Miscellaneousd | 16 (2.4) |
| Antidysrhythmics and other cardiovascular agents | 27 (4.1) |
| Atorvastatin | 8 (1.2) |
| Simvastatin | 6 (1.0) |
| Miscellaneouse | 13 (2.0) |
| Diuretics | 25 (3.8) |
| Hydrochlorothiazide | 16 2.4) |
| Furosemide | 5 (0.8) |
| Miscellaneousf | 4 (0.6) |
| Angiotensin receptor blockers | 9 (1.4) |
| Losartan | 5 (0.8) |
| Miscellaneousg | 4 (0.6) |
| Class total | 654 (100) |
aIncludes nebivolol, bisoprolol, nadolol, and timolol
bIncludes nicardipine
cIncludes benazepril, enalapril, and quinapril
dIncludes hydralazine, nitroprusside, isosorbide, nitroglycerin, terazosin, alkyl nitrite, doxazosin, and minoxidil
eIncludes flecainide, sotalol, amiodarone, midodrine, cardiovascular agent unspecified, quinidine, pravastatin
fIncludes chlorthalidone, acetazolamide, spironolactone
gIncludes valsartan, irbesartan, olmesartan