Table 35.
Antidotal therapy administered in ToxIC in 2016
| N (%)a | |
|---|---|
| N-Acetylcysteine | 974 (27.5) |
| Naloxone/nalmefene | 705 (19.9) |
| Sodium bicarbonate | 421 (11.9) |
| Thiamine | 250 (7.1) |
| Folate | 201 (5.7) |
| Physostigmine | 147 (4.2) |
| Fomepizole | 119 (3.4) |
| Calcium | 110 (3.1) |
| Glucagon | 98 (2.8) |
| Flumazenil | 63 (1.8) |
| Cyproheptadine | 58 (1.6) |
| Vitamin K | 51 (1.4) |
| Atropine | 47 (1.3) |
| L-Carnitine | 44 (1.3) |
| Insulin-euglycemic therapy | 44 (1.3) |
| Octreotide | 44 (1.3) |
| Fab for digoxin | 34 (1.0) |
| Lipid resuscitation | 25 (0.8) |
| Pyridoxine | 26 (0.7) |
| Hydroxocobalamin | 17 (0.5) |
| Methylene blue | 14 (0.4) |
| Dantrolene | 9 (0.3) |
| 2-PAM | 7 (0.2) |
| Bromocriptine | 6 (0.2) |
| Thiosulfate | 6 (0.2) |
| Anticoagulation reversal | 5 (0.1) |
| Botulinum antitoxin | 3 (0.1) |
| Ethanol | 2 (0.1) |
| Nitrites | 2 (0.1) |
| Coagulation factor replacement | 1 (<0.1) |
| Protamine | 1 (<0.1) |
| Total | 3540 (100) |
aPercentages are out of the total number of antidotes administered (N = 3540); 3047 cases (35.7% of total Registry cases) received at least one antidote; some cases involve multiple antidotes