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. 2017 Aug 24;7:9376. doi: 10.1038/s41598-017-09175-4

Figure 4.

Figure 4

Percentage of drug incorporated and released. The histogram (A) reports the percentage of drugs estimated by biological dosage in the conditioned medium (CM) and cell lysate (LYS). The box (B) reports the IC50 value of the drugs (ng/ml) of the conditioned medium and lysate (µl/well) used to estimate the amount of drugs incorporated (LYS, ng total) or released (CM, ng total) by GinPa-MSCs. Values are expressed as mean ± standard deviation (SD) of three independent experiments. The box (C) reports the amount of drugs potentially delivered by 106 GinPa-MSCs and their ratio to the IC50 values of each drug. CDR = Single cell drug release.