Fig. 7.
Physical performance depends on endothelial Piezo1. Voluntary running wheel data for control and Piezo1ΔEC genotypes from the dark cycle (active period) showing distance run on the wheel a, percentage time for which mice were active on the wheel b and the number of active bouts of exercise c (n = 12 mice per group). d As for c but summary analysis for all bouts of activity. e For the same mice analysed in a–d, changes in body weight during the 12 days prior to and 7 days after access to the wheel (n = 12 mice per group). Averaged data are displayed as mean ± s.e.m. Data sets are compared by t-test. Statistical significance is indicated by *P < 0.05