FIG 4.

Phylogeography of coxsackievirus A16 clade D. Temporal distribution of lineages (A) and pattern of spatial spread assessed among French cities (B). Map source: Google, 2016. See the legend to Fig. 3 for details. R1 indicates a probable intertypic recombination event associated with the emergence of genogroup D and R3 an intratypic recombinant (see Fig. 5C). ALB, Aix les Bains; BSC, Bagnols sur Ceze; CF, Clermont-Ferrand; LYO, Lyon; MET, Metz; PAR, Paris; PER, Peru; ROU, Rouen; SBR, Saint-Brieuc; STR, Strasbourg; TLS, Toulouse; VES, Vesoul.