FIG 6.

Synergistic anti-HIV effects of unconjugated peptide inhibitors. The synergistic inhibition by inhibitors of HIV-1 pseudoviruses was determined by single-cycle infection assay. Peptides were tested individually and in combination at a fixed molar ratio achieving equivalent IC₅₀s. T20/HP23 ratios, 5:1 (A), 1:1 (B), and 1:2 (C); T20/T1249 ratios, 3:1 (D), 1:1 (E), and 3:1 (F). Each sample was tested in triplicate, and the experiment was repeated 3 times. The error bars indicate SD.