FIG 9.

IFNAR-mediated antiviral signaling protects mice infected with WR but not those infected with WRΔA26. WT mice (IFNAR^+/+ sibling control; n = 5 in panels A and B) and IFNAR^−/− mice (n = 5 in panels C and D) were infected intranasally with 10⁴ PFU of WR or WRΔA26 per mouse and monitored daily for body weight loss (A and C) and mortality (B and D). Statistical analyses of body weight change (A and C) and survival curves (B and D) were performed as described in the legend to Fig. 8A and B. *, P < 0.05.