TABLE 1.
Characteristics of healthy adult subjects receiving omadacycline and tigecyclinea
| Treatment | Sexb (no. of subjects) | Age (yr) | Ht (cm) | Wt (kg) | CLCRc (ml/min) | Total cell count in BAL fluid (no. of cells/mm3) | % of macrophages in BAL fluid |
|---|---|---|---|---|---|---|---|
| Omadacycline (n = 41) | M (28), F (13) | 38 ± 10 | 173 ± 10 | 78.0 ± 12.4 | 110 ± 21 | 128 ± 93 | 82 ± 17 |
| Tigecycline (n = 17) | M (13), F (4) | 40 ± 10 | 174 ± 10 | 78.6 ± 12.4 | 109 ± 26 | 154 ± 89 | 91 ± 5 |
a
All data except for sex are expressed as the mean ± SD.
b
M, male; F, female.
c
CLCR, estimated creatinine clearance.