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Checkerboard assay results for disulfiram synergy with vancomycin in three VRSA strains
| Strain | MIC (μg/ml) |
FICa | ΣFICb | ||
|---|---|---|---|---|---|
| VAN | DSF | VAN/DSF | |||
| HIP14300 | >128 | 16 | 16/0.5 | 0.03 | <0.16 (S) |
| AIS 2006045 | >128 | 16 | 8/1 | 0.06 | <0.12 (S) |
| AIS 1000505 | >128 | 16 | 4/1 | 0.06 | <0.09 (S) |
That is, the lowest FIC measurement of DSF in combination with VAN.
That is, the lowest ΣFIC measurement. Results: synergy (S), ≤0.5; indifferent (I), 0.5 < to ≤4; antagonism (A), >4.
