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AST levels in plasma during treatment. The effects of different treatments on organ damage were estimated by measuring AST levels in plasma 48 h after bacterial inoculation in mice treated with levofloxacin alone or in combination with EM703. The results are expressed as the mean ± SEM (four mice in each group). The Kruskal-Wallis nonparametric test, with Dunn's post hoc test for multiple comparisons, was used. *, P ≤ 0.05.
