TABLE 1.
Treatment | Total cells |
Macrophages |
Neutrophils |
Eosinophils |
Lymphocytes |
|||||
---|---|---|---|---|---|---|---|---|---|---|
Cells/ml (mean ± SEM) | Pa | Cells/ml (mean ± SEM) | P | Cells/ml (mean ± SEM) | P | Cells/ml (mean ± SEM) | P | Cells/ml (mean ± SEM) | P | |
Levofloxacin alone | 5.0 × 105 ± 9.0 × 104 | 3.9 × 104 ± 8.2 × 103 | 4.5 × 105 ± 8.1 × 104 | 8.5 × 103 ± 3.6 × 103 | 1.3 × 104 ± 3.4 × 103 | |||||
Levofloxacin plus EM703 at −24 h | 1.1 × 106 ± 1.1 × 105 | 0.0002 | 4.2 × 105 ± 7.9 × 104 | <0.0001 | 9.6 × 105 ± 8.8 × 104 | 0.0002 | 1.1 × 104 ± 4.3 × 103 | 0.9834 | 2.1 × 104 ± 5.8 × 103 | >0.9999 |
Levofloxacin plus EM703 at 0 h | 9.0 × 105 ± 1.1 × 105 | 0.0381 | 1.6 × 105 ± 3.6 × 104 | 0.0263 | 7.4 × 105 ± 1.0 × 105 | 0.0544 | 1.2 × 104 ± 4.0 × 103 | >0.9999 | 1.4 × 104 ± 2.7 × 103 | 0.5298 |
P values were calculated using levofloxacin alone as a control.