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. 2017 Aug 24;61(9):e00612-17. doi: 10.1128/AAC.00612-17

TABLE 2.

F. tularensis susceptibility values for 30 strains

Antibiotic Range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml)
Amikacin ≤0.03 to 8 1 2
Gentamicin ≤0.03 to 1 0.25 0.5
Netilmicin ≤0.03 to 0.5 0.25 0.25
Streptomycin ≤0.03 to >64 4 8
Tobramycin ≤0.03 to 0.5 0.12 0.25
Azithromycin 0.12 to 16 1 1
Cethromycin ≤0.03 to 8 0.12 0.5
Telithromycin ≤0.03 to 16 0.25 1
Clarithromycin ≤0.03 to >64 0.5 4
Solithromycin ≤0.015 to 4 0.03 2
Garenoxacin ≤0.004 to 0.12 0.008 0.03
Ciprofloxacin 0.015 to 0.25 0.12 0.25
Gatifloxacin ≤0.004 to 1 0.015 0.06
Gemifloxacin ≤0.004 to 0.12 0.008 0.03
Levofloxacin 0.008 to 0.25 0.03 0.06
Moxifloxacin ≤0.004 to 0.12 0.008 0.06
Nalidixic acid 0.25 to 16 0.5 2
Ofloxacin 0.015 to 0.06 0.015 0.06
Sparfloxacin ≤0.004 to 0.06 ≤0.004 0.12
Novobiocin ≤0.03 to 1 0.06 0.5
Amoxicillin-clavulanate (2:1) 0.5 to >64 16 16
Amoxicillin 4 to >64 >64 >64
Ampicillin 4 to >64 >64 >64
Penicillin G 2 to >64 >64 >64
Piperacillin 0.03 to >64 32 >64
Imipenem 0.06 to >64 0.12 8
Ertapenem 0.06 to >64 1 8
Faropenem 0.12 to 16 2 4
Meropenem 0.12 to >64 1 16
Cefepime 0.12 to >64 4 16
Ceftazidime 0.03 to >64 0.12 1
Cefotaxime 0.03 to >64 1 2
Cefotetan 0.25 to >64 2 8
Cefuroxime 0.5 to >64 4 16
Cefazolin 0.5 to >64 >64 >64
Ceftriaxone ≤0.03 to >64 0.25 2
Ceftaroline 0.06 to >8 0.25 8
Aztreonam 0.5 to >64 2 8
Sulfamethoxazole 4 to >256 128 >256
Co-trimoxazole (19:1) 0.25 to 8 1 4
Trimethoprim 0.25 to >64 4 16
Doxycycline ≤0.03 to 4 0.12 0.25
Tetracycline ≤0.03 to 1 0.12 0.25
Tigecycline ≤0.03 to 0.5 0.12 0.25
Rifampin ≤0.03 to 2 0.12 0.5
Chloramphenicol 0.25 to 8 2 4
Fusidic acid ≤0.03 to 32 2 8