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. 2017 Aug 24;61(9):e00700-17. doi: 10.1128/AAC.00700-17

TABLE 2.

Extrapolated %f TMICa achieved with a human exposure of 2 g cefiderocol every 8 h as a 1- or 3-h infusion in infected rats

Cefiderocol MIC (μg/ml) %f TMIC with an infusion time of:
1 h 3 h
0.125 100 100
0.25 100 100
0.5 100 100
1 100 100
2 100 100
4 75 100
8 50 100
a

%fTMIC, percentage of the dosing interval during which free drug concentrations are above the MIC.