TABLE 3.
Control and combination antimicrobial groupsa
| Treatment group | Drug | Dosage (mg/kg body weight) |
|---|---|---|
| SWI control (no treatment control) | Vehicle (SWI) | q12h |
| Ciprofloxacin control | Ciprofloxacin | 30, q12h |
| 1 | Ciprofloxacin | 30, q12h |
| Meropenem | 100, q6h | |
| Linezolid | 50, q12h | |
| 2 | Ciprofloxacin | 30, q12h |
| Meropenem | 100, q6h | |
| Clindamycin | 50, q6h | |
| 3 | Ciprofloxacin | 30, q12h |
| Meropenem | 100, q6h | |
| Rifampin | 50, q6h | |
| 4 | Ciprofloxacin | 30, q12h |
| Meropenem | 100, q6h | |
| Doxycycline | 40, q12h | |
| 5 | Ciprofloxacin | 30, q12h |
| Penicillin G | 100, q6h | |
| Linezolid | 50, q12h | |
| 6 | Ciprofloxacin | 30, q12h |
| Penicillin G | 100, q6h | |
| Doxycycline | 40, q12h | |
| 7 | Ciprofloxacin | 30, q12h |
| Rifampin | 50, q6h | |
| Linezolid | 50, q12h | |
| 8 | Ciprofloxacin | 30, q12h |
| Clindamycin | 50, q6h | |
| Rifampin | 50, q6h |
a
Intraperitoneal administration of the antibiotics in mice commenced at 36 h for 14 days at the indicated dosages.