TABLE 2.
MBCs of different antimicrobial agents for selected Borrelia burgdorferi sensu lato and relapsing-fever Borrelia strainsa
| Antimicrobial | MBC rangeb (mg/liter) |
||||
|---|---|---|---|---|---|
|
B. burgdorferi sensu lato |
Relapsing-fever Borrelia strains |
||||
| PKo | B31 | HT31 | LB-2001 | HS1 | |
| Amoxicillin | 16–32 | 64 | 128 | 32 | >64 |
| Doxycycline | 8–16 | >16 | 4 | 1–2 | >4 |
| Ceftriaxone | >0.5 | 0.25–>1 | >1 | 1–2 | 2 |
| Azithromycin | 0.025 | >0.05 | >0.0125 | 0.0125 | ≥0.05 |
| Amikacin | 256–512 | 512 | 64 | 512 | 32–64 |
a
MBCs, minimum bactericidal concentrations. PKo, B. afzelii reference strain; B31, B. burgdorferi sensu stricto reference strain; HT31, B. miyamotoi tick isolate (Japan); LB-2001, B. miyamotoi tick isolate (United States); HS1, B. hermsii reference strain.
b
Ranges are results of tests that were conducted in quadruplicate.