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Pharmacokinetic parameters for nafithromycin at 800 mg in plasmaa
| Dose | Cmax (mg/liter) | Tmax (h) | AUCb (mg · h/liter) | t1/2 (h) | V/F (liters) | CL/F (liters/h) |
|---|---|---|---|---|---|---|
| First | 1.015 ± 0.314 | 3.97 ± 1.30 | 12.89 ± 3.77 | 7.69 ± 1.14 | 731 ± 190 | 67.3 ± 21.3 |
| Third | 1.387 ± 0.361 | 3.69 ± 1.28 | 16.64 ± 4.58 | 9.05 ± 1.72 | 666 ± 201 | 52.4 ± 18.5 |
Data are expressed as the mean ± SD.
AUC for the first dose was AUC0–∞, and AUC for the third dose was AUC0–24.
