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Mouse plasms levels of VT-1161 measured by LC/MS-MS. Plasma samples (n = 19 mice per group from two independent experiments with similar results) collected on day +4 (i.e., 4 days after prophylaxis treatment and 4 h after the last dose administered on day +4 for the continuous therapy). *, P < 0.0001 by Wilcoxon rank sum test.
