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Pharmacokinetics of AMB in the blood of L. major-infected mice treated with DSHemsPC-AMB-Lip, AmBisome, or Fungizone in a model of established CL. BALB/c mice were infected in the footpad with 2 × 106 stationary-phase L. major promastigotes. The serum AMB concentrations were significantly different between Fungizone-treated mice and DSHemsPC-AMB-Lip- and AmBisome-treated mice (**, P ≤ 0.01).
