Schematic representation of target sites of toxins produced by A. alternata. The putative target site of ACT-toxins in tangerine is the plasma membrane. After the infection of citrus leaves, induction of fast lipid peroxidation and accumulation of hydrogen peroxide (H2O2) occurs, resulting in cell death. The target of ACR-toxin is the mitochondrion, which after contact with the host plant causes a rapid increase in electrolyte leakage and consequent cell death. Ch, chloroplast; ER, endoplasmic reticulum; Gl, Golgi apparatus; Mt, mitochondrion; Nu, nucleus; Pm, plasma membrane; Va, vacuole.