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. 2017 Aug 16;35(35Part B):4561–4568. doi: 10.1016/j.vaccine.2017.07.019

Table 3.

The incidence of invasive pneumococcal disease (IPD) pre- and 10 years post-vaccination. The table presents the posterior predictive mean values with the 95% predictive intervals.

Age group (years) Pre-vaccination IPD incidence (/100,000/year)
10 years post-vaccination IPD incidence (/100,000/year)

VT Strong NVT Weak NVT VT Strong NVT Weak NVT IRRa
<1 67.0 21.0 7.1 6.7 (1.1, 15.1) 37.0 (29.5, 50.4) 11.6 (9.4, 15.6) 0.59 (0.51, 0.72)
1–5 39.3 5.1 0.7 6.4 (1.2, 14.7) 7.8 (6.5, 10.0) 1.1 (0.9, 1.4) 0.34 (0.24, 0.50)
6–14 7.3 1.0 0.0 1.4 (0.3, 3.3) 1.2 (1.1, 1.5) 0.0 (0.0, 0.0) 0.33 (0.20, 0.54)
15–20 1.0 0.0 0.0 0.3 (0.1, 0.5) 0.0 (0.0, 0.0) 0.0 (0.0, 0.0) 0.26 (0.05, 0.54)
21–49 4.2 0.9 0.0 1.2 (0.2, 2.3) 1.1 (1.0, 1.3) 0.0 (0.0, 0.0) 0.45 (0.28, 0.66)
≥50 9.2 2.8 4.1 2.5 (0.5, 5.1) 3.4 (3.1, 3.9) 5.3 (4.7, 6.3) 0.71 (0.60, 0.82)



All ages 14.8 2.7 0.9 2.5 (0.5, 5.6) 4.2 (3.5, 5.3) 1.3 (1.1, 1.6) 0.44 (0.34, 0.56)
a

The incidence rate ratio (IRR) is between the overall IPD incidence before vaccination and the IPD incidence 10 years post vaccination.