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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: Stat Med. 2017 Apr 6;36(15):2323–2332. doi: 10.1002/sim.7295

Table I.

An example of four doses in three completely ordered groups.

Dose level
Group Prognosis 1 2 3 4
3 Severe π31 π32 π33 π34
2 Moderate π21 π22 π23 π24
1 None π11 π12 π13 π14

‘π’ denotes the probability of DLT at each group–dose combination. DLT, dose-limiting toxicity.