Figure 3.

(A) Free energy profile of myristamide insertion from water into a PC:PG (4:1) membrane, showing the dependence of the free energy on the distance of the center of mass of myristamide from the central plane of the bilayer. The robustness of this result was verified with respect to the choice of the force field and the set of initial geometries (Figure S4). (B) Free energy profile of the membrane detachment of a non-myristoylated recoverin, calculated along the distance between the center of mass of the protein and the central plane of the bilayer.