Table 3.
Secondary outcomes in women reciving calcium and cholecalciferol (vitamin D3) supplementation (intervention group) and those receiving only advice on diet and prevention of falls. Values are percentages (numbers) unless stated otherwise
| Secondary outcome measures | Intervention group (n=1321) | Control group (n=1993) | Adjusted odds ratio*(95% Cl) | Adjusted mean difference*(95% Cl) | P value |
|---|---|---|---|---|---|
| Deaths: | |||||
| Unequally allocated group†
|
3.8 (27/714)
|
3.7 (51/1391)
|
1.26 (0.87 to 1.83) | — | 0.22 |
| Equally allocated group | 4.9 (30/607) | 2.8 (17/602) | |||
| ≥1 hospital admissions in first 12 months: | |||||
| Unequally allocated group
|
41.7 (220/528)
|
42.8 (481/1124)
|
0.86 (0.72 to 1.03) | — | 0.10 |
| Equally allocated group | 38.2 (126/330) | 46.7 (189/405) | |||
| ≥1 visits to doctor in first 12 months: | |||||
| Unequally allocated group
|
80.4 (430/535)
|
80.5 (917/1139)
|
0.84 (0.67 to 1.04) | — | 0.11 |
| Equally allocated group | 76.5 (251/328) | 82.8 (346/418) | |||
| SF-12 (SD) scores at 12 months | |||||
| Physical component: | |||||
| Unequally allocated group
|
41.66 (11.74)
|
41.20 (11.92)
|
— | −0.152 (−0.10 to 0.7) | — |
| Equally allocated group | 41.33 (11.38) | 39.68 (12.05) | |||
| Mental health component: | |||||
| Unequally allocated group
|
52.02 (9.17)
|
51.87 (9.23)
|
— | 0.03 (−0.04 to 0.97) | — |
| Equally allocated group | 51.73 (9.23) | 50.77 (10.00) |
*
Adjusted for practice and age.
†
Two women randomised to control group for every one allocated to treatment group.