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Effect of tolvaptan on urinary excretion of AQP2. (A) Evaluation of urinary AQP2 in patient 1 affected by SIAD after 12‐h and 24‐h tolvaptan administration. (B) Effect of tolvaptan treatment on natraemia of patient 1. (C) Evaluation of urinary AQP2 in patient 2 affected by SIAD after 12‐h and 24‐h tolvaptan administration. (D) Effect of tolvaptan treatment on natraemia of patient 2.
