Figure 7.

A schematic summary of the suppression of hypoxia‐induced VSMC growth by HDIs involving eNOS–NO activation. The point arrows are used to indicate promotion effects. The round‐headed arrows are used to indicate suppression. The parts with dotted lines are shown as speculative views. The abbreviations are described as follows: HDI, histone deacetylase inhibitor; Ac‐H3K9, acetylated histone H3 at lysine 9; Ac‐H4K12/8, acetylated histone H4 at lysine 12/lysine 8; eNOS, endothelial nitric oxide synthase.