Skip to main content
. 2017 Feb 28;21(9):1791–1802. doi: 10.1111/jcmm.13100

Figure 6.

Figure 6

CBX attenuated TRPV4‐mediated oxidative responses. (A–B) Primarily cultured urothelial cells were exposed to 10 μM 4α‐PDD in the presence or absence of 10 μM CBX for 12 hrs. Afterwards, the cells were stained with PI (A), and cell supernatants were collected for LDH assay (B). Data are expressed as mean ± S.E. (n = 3). # P < 0.05. (C–D) Effect of CBX on 4α‐PDD‐induced protein carbonylation and P38 activation. Urothelial cells were exposed to 10 μM 4α‐PDD in the presence or absence of CBX for 6 hrs. Cell lysates were assayed for carbonylated proteins (C) and p38 phosphorylation (D).