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. 2017 Mar 27;21(9):2211–2222. doi: 10.1111/jcmm.13144

Figure 5.

Figure 5

Effect of cigarette smoke exposure and Let‐7f treatment on TGF‐βR1/ALK5 pathway. Representative images and quantification of Western blots of ALK5, p‐SMAD2/3, p‐SMAD1/5 and PAI‐1 in the ischaemic muscles of mice (AD) and in HUVECs (EH) after different treatments. Protein expression was normalized to β‐actin. Data are mean ± S.E.M. n = 4/group (mice) and n = 3/group (HUVECs). *P < 0.05 versus CTL+mimic C, #P < 0.05 versus MES+ mimic C or CSE+mimic C.