Table 3.

Effect of ethanolic extract of E. hirta whole plant on excision wound in alloxan induced diabetic rats

Group/ Post wounding days	Wound area (cm2)					% of wound contraction at the end of the study
	1st day	4th day	8th day	12th day	16th day
Group I	N/A	N/A	N/A	N/A	N/A	N/A
Group II	4.90 ± 1.13	4. 90 ± 1.20	4.85 ± 0.88	4.72 ± 0.89	4.60 ± 0.93	6.12
Group III	4.90 ± 1.11	4.83 ± 1.05†	4.58 ± 1.17†	3.76 ± 0.59†	3.14 ± 0.36†	35.92
Group IV	4.90 ± 1.03	4.70 ± 0.91†	4.50 ± 0.86†	3.23 ± 0.65†	2.71 ± 0.40*	44.69
Group V	4.90 ± 1.10	4.58 ± 1.07†	4.16 ± 0.88†	2.48 ± 0.33*	1.89 ± 0.35**	61.42
Group VI	4.90 ± 1.12	4.51 ± 1.01†	4.35 ± 0.76†	3.26 ± 0.33†	2.95 ± 0.54*	39.79
Group VII	4.90 ± 1.16	4.83 ± 1.21†	4.55 ± 0.73†	3.92 ± 0.58†	3.29 ± 0.37†	32.86
Group VIII	4.90 ± 0.88	4.75 ± 1.03†	4.47 ± 0.68†	3.41 ± 0.56†	3.12 ± 0.49†	36.32

Each value is Mean ± S.E.M (n = 3). (*) indicates statistically significant difference from the diabetic wound control using ANOVA, followed by Dunnett’s multiple comparison test (^** p < 0.01). (†) indicates statistically no significant difference from the diabetic wound control using ANOVA, followed by Dunnett’s multiple comparison test (p > 0.05). Group I = normal control, Group II = Diabetic wound control, Group III = Diabetic wound control +100 mg ethanolic extract of E. hirta, Group IV = Diabetic wound control +200 mg ethanolic extract of E. hirta, Group V = Diabetic wound control +400 mg ethanolic extract of E. hirta, Group VI = Diabetic wound control +5% Povidone iodine, Group VII = Diabetic wound control +5% ethanolic extract of E. hirta, Group VIII = Diabetic wound control +10% ethanolic extract of E. hirta