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Advantages and disadvantages of analytical strategies
| Regression | Stratification | |
|---|---|---|
| Advantages | Familiar to researchers
|
Can focus on key confounders
|
| Uses all the data
|
Can be easily used to assess presence of effect modification
|
|
| Standard software available | Standard software available | |
| Disadvantages | Comparability of treatment groups difficult to assess
|
Imbalance may still be present within strata
|
| Involves extrapolation | Can reduce power |
