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. 2017 May 30;35(35):4461–4464. doi: 10.1016/j.vaccine.2017.04.085

Table 1.

Priority pathogens for vaccine development. The descriptions here are intended to give an overview of the diseases with outbreak potential and the information contained is not exhaustive. More detailed, and updated information may be obtained from the WHO website http://www.who.int/mediacentre/factsheets/en/.

Disease Characteristics of disease Insect vector Main geographic location Livestock affected
Ebola virus disease Haemorraghic fever None Central and West Africa None, reservoir in wild animals
Marburg Haemorraghic fever None Angola, Democratic Republic of the Congo, Kenya, and Uganda None, reservoir in wild animals
Lassa fever Haemorraghic fever None Benin, Ghana, Guinea, Liberia, Mali, Sierra Leone, and Nigeria None, reservoir in rodents
Crimean Congo haemorrhagic fever Haemorraghic fever Ticks Africa, the Balkans, the Middle East and Asia, in countries south of the 50th parallel north Cattle, sheep, goats, ostriches
MERS Chronic respiratory syndrome None Middle East Camels infected but illness not apparent
SARS Acute respiratory syndrome None China None, reservoir in wild animals
Nipah Acute respiratory syndrome, enchephalitis None Malaysia, Bangladesh, India Pigs, reservoir in bats
Rift Valley fever Haemorraghic fever Aedes and Culex mosquitoes Africa, Middle East Sheep, cattle, goats, camels
Zika Generally mild, but causes severe birth defects Aedes mosquitoes South America None
HHS Vulnerability Disclosure