Table 1.
Priority pathogens for vaccine development. The descriptions here are intended to give an overview of the diseases with outbreak potential and the information contained is not exhaustive. More detailed, and updated information may be obtained from the WHO website http://www.who.int/mediacentre/factsheets/en/.
Disease | Characteristics of disease | Insect vector | Main geographic location | Livestock affected |
---|---|---|---|---|
Ebola virus disease | Haemorraghic fever | None | Central and West Africa | None, reservoir in wild animals |
Marburg | Haemorraghic fever | None | Angola, Democratic Republic of the Congo, Kenya, and Uganda | None, reservoir in wild animals |
Lassa fever | Haemorraghic fever | None | Benin, Ghana, Guinea, Liberia, Mali, Sierra Leone, and Nigeria | None, reservoir in rodents |
Crimean Congo haemorrhagic fever | Haemorraghic fever | Ticks | Africa, the Balkans, the Middle East and Asia, in countries south of the 50th parallel north | Cattle, sheep, goats, ostriches |
MERS | Chronic respiratory syndrome | None | Middle East | Camels infected but illness not apparent |
SARS | Acute respiratory syndrome | None | China | None, reservoir in wild animals |
Nipah | Acute respiratory syndrome, enchephalitis | None | Malaysia, Bangladesh, India | Pigs, reservoir in bats |
Rift Valley fever | Haemorraghic fever | Aedes and Culex mosquitoes | Africa, Middle East | Sheep, cattle, goats, camels |
Zika | Generally mild, but causes severe birth defects | Aedes mosquitoes | South America | None |