Table 4.
Pathology characteristics in IG-IMRT and 3DCRT groups
| Characteristics | IG-IMRT n = 45 |
3DCRT n = 99 |
P |
|---|---|---|---|
| Pathologic tumor depth | 0.221 | ||
| ypT0 | 8 (17.8) | 17 (17.2) | |
| ypT1 | 2 (4.4) | 5 (5.1) | |
| ypT2 | 17 (37.8) | 26 (26.3) | |
| ypT3 | 17 (37.8) | 44 (44.4) | |
| pT4 | 1 (2.2) | 7 (7) | |
| Pathologic lymph node metastasis | 0.832 | ||
| pN0 | 34 (75.6) | 70 (70.7) | |
| ypN1 | 8 (17.8) | 21 (21.2) | |
| ypN2 | 3 (6.6) | 8 (8.1) | |
| Pathologic complete response | 8 (17.8) | 15 (15.1) | 0.527 |
| Median number of resected nodesa | 12 (0–21) | 10 (0–28) | 0.795b |
| Median number of involved nodesa | 0 (0–9) | 0 (0–13) | 0.321b |
| Tumor regression grade | 0.092 | ||
| 0 | 1 (2.2) | 8 (8.1) | |
| 1 | 6 (13.3) | 24 (24.2) | |
| 2 | 8 (17.8) | 24 (24.2) | |
| 3 | 22 (48.9) | 26 (26.3) | |
| 4 | 8 (17.8) | 17 (17.2) | |
| Treatment responsec | 0.071 | ||
| Favorable | 30 (66.7) | 43 (43.5) | |
| Unfavorable | 15 (33.3) | 56 (56.5) | |
| Surgical distal margin | 0.383 | ||
| Negative | 42 (93.3) | 92 (92.9) | |
| Positive | 3 (6.7) | 7 (7.1) | |
| Circumferential resection margin | 0.376 | ||
| Negative | 43 (95.6) | 96 (96.9) | |
| Positive | 2 (4.4) | 3 (3.1) | |
| Perineural invasion | 0.136 | ||
| Negative | 35 (77.8) | 65 (65.6) | |
| Positive | 10 (22.2) | 34 (34.4) | |
| Lymphovascular invasion | 0.699 | ||
| Negative | 38 (84.4) | 86 (86.8) | |
| Positive | 7 (15.6) | 13 (13.2) | |
| Tumor differentiation | 0.823 | ||
| Well | 6 (13.3) | 20 (20.2) | |
| Moderately | 36 (80.0) | 77 (77.8) | |
| Poorly | 3 (6.7) | 2 (2.0) |
Data are presented as n (%), unless otherwise indicated.
aMedian (range).
bt-test.
cFavorable treatment responses included TRG 3 or 4; unfavorable treatment responses included TRG 0–2. IG-IMRT = image-guided intensity-modulated radiotherapy, 3DCRT = 3D conformal radiotherapy.