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. 2017 Aug 25;5:108. doi: 10.1186/s40168-017-0316-0

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — β-Diversity of 824 samples based on unweighted UniFrac distances, by number of O. formigenes OTUs detected. a–d Visualization of β-diversity ordination through PCoA of all 824 samples meeting the inclusion criteria (Additional file 5: Table S2) (a), 604 US samples (b), 144 UK or Ireland samples (c), and the rest of the 70 samples (d). Samples with 0, 1, or 2 O. formigenes OTUs are represented in blue, green, and red dots. Ellipses were drawn with ggplot2 stat_ellipse function using multivariate t-distribution. By Qiime PERMANOVA test based on 1000 permutations, *p value <0.05. e–h Bar plots (mean ± S.E.M) of intra- and intergroup pairwise sample UniFrac distance for all samples (e), 604 US samples (f), 144 UK or Ireland (g) samples, or the remaining 70 samples (h). By Bonferroni-corrected t tests, *p < 0.05